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1

Insulin Degradation by Hepatocytes in Primary Culture*

DUCKWORTH, WILLIAM C., RUNYAN, KEITH R., WRIGHT, REBA K., HALBAN, PHILIPPE A., SOLOMON, SOLOMON S.

Journal:

Year:

1981

Language:

english

File:

PDF, 709 KB

english, 1981

2

The Possible Importance of Contact between Pancreatic Islet Cells for the Control of Insulin Release*

HALBAN, PHILIPPE A., WOLLHEIM, CLAES B., BLONDEL, BENIGNA, MEDA, PAOLO, NIESOR, ERIC N., MINTZ, DANIEL H.

Journal:

Year:

1982

Language:

english

File:

PDF, 2.29 MB

english, 1982

3

Publish and flourish: seasonal advice to our readers

Philippe Halban

Journal:

Year:

1995

Language:

english

File:

PDF, 263 KB

english, 1995

4

Introduction

Paul Czernichow, Philippe Halban, Caroline Lurie, J. Denis McGarry, Ali Naji, Christos Bartsocas

Journal:

Year:

1997

Language:

english

File:

PDF, 45 KB

english, 1997

5

Thank you Vienna—over to you, Bristol

Philippe Halban

Journal:

Year:

2004

Language:

english

File:

PDF, 130 KB

english, 2004

6

Sorting Ourselves Out: Seeking Consensus on Trafficking in the Beta-Cell

Peter Arvan, Philippe A. Halban

Journal:

Year:

2004

Language:

english

File:

PDF, 220 KB

english, 2004

7

Munc 18-1 and Granuphilin Collaborate During Insulin Granule Exocytosis

Alejandra Tomas, Paolo Meda, Romano Regazzi, Jeffrey E. Pessin, Philippe A. Halban

Journal:

Year:

2008

Language:

english

File:

PDF, 3.58 MB

english, 2008

8

Regulation of Insulin Secretion by Phosphatidylinositol-4,5-Bisphosphate

Alejandra Tomas, Barbara Yermen, Romano Regazzi, Jeffrey E. Pessin, Philippe A. Halban

Journal:

Year:

2010

Language:

english

File:

PDF, 1.81 MB

english, 2010

9

Cellular sources of new pancreatic β cells and therapeutic implications for regenerative medicine

Halban, Philippe A.

Journal:

Nature Cell Biology

Year:

2004

Language:

english

File:

PDF, 269 KB

english, 2004

10

Diabetes research investment in the European Union

Halban, Philippe A, Ferrannini, Ele, Nerup, Jørn

Journal:

Nature Medicine

Year:

2006

Language:

english

File:

PDF, 672 KB

english, 2006

11

Ectopic expression of the beta-cell specific transcription factor Pdx1 inhibits glucagon gene transcription

Ritz-Laser, B., Gauthier, B. R., Estreicher, A., Mamin, A., Brun, T., Ris, F., Salmon, P., Halban, P. A., Trono, D., Philippe, J.

Journal:

Year:

2003

Language:

english

File:

PDF, 429 KB

english, 2003

12

Identification and Characterization of α3β1 Integrin on Primary and Transformed Rat Islet Cells

Salomé Kantengwa, Dany Baetens, Karin Sadoul, Clayton A. Buck, Philippe A. Halban, Dominique G. Rouiller

Journal:

Experimental Cell Research

Year:

1997

Language:

english

File:

PDF, 840 KB

english, 1997

13

Trafficking/sorting and granule biogenesis in theβ-cell

Miguel Molinete, Jean-Claude Irminger, Sharon A. Tooze, Philippe A. Halban

Journal:

Seminars in Cell & Developmental Biology

Year:

2000

Language:

english

File:

PDF, 278 KB

english, 2000

14

Long-term exposure of isolated pancreatic islets to mannoheptulose: Evidence for insulin degradation in the β cell

Philippe A. Halban, Claes B. Wollheim, Benigna Blondel, Albert E. Renold

Journal:

Biochemical Pharmacology

Year:

1980

Language:

english

File:

PDF, 1.55 MB

english, 1980

15

Uvomorulin mediates calcium-dependent aggregation of islet cells, whereas calcium-independent cell adhesion molecules distinguish between islet cell types

Dominique G. Rouiller, Vincenzo Cirulli, Philippe A. Halban

Journal:

Developmental Biology

Year:

1991

Language:

english

File:

PDF, 4.88 MB

english, 1991

16

Differences in aggregation properties and levels of the neural cell adhesion molecule (NCAM) between islet cell types

Dominique G. Rouiller, Vincenzino Cirulli, Philippe A. Halban

Journal:

Experimental Cell Research

Year:

1990

Language:

english

File:

PDF, 2.33 MB

english, 1990

17

Glucose stimulates the biosynthesis of rat I and II insulin to an equal extent in isolated pancreatic islets

Christopher J. Rhodes, Christine A. Lucas, Philippe A. Halban

Journal:

Year:

1987

Language:

english

File:

PDF, 258 KB

english, 1987

18

Oxidation of rat insulin II, but not I, leads to anomalous elution profiles upon HPLC analysis of insulin-related peptides

David Gross, Anne Skvorak, Grant Hendrick, Gordon Weir, Lydia Villa-Komaroff, Philippe Halban

Journal:

Year:

1988

Language:

english

File:

PDF, 264 KB

english, 1988

19

Towards a perfect beta cell replacement

Philippe A. Halban

Journal:

Seminars in Cell & Developmental Biology

Year:

2004

Language:

english

File:

PDF, 28 KB

english, 2004

20

Cytokine production by islets in health and diabetes: cellular origin, regulation and function

Marc Y. Donath, Marianne Böni-Schnetzler, Helga Ellingsgaard, Philippe A. Halban, Jan A. Ehses

Journal:

Trends in Endocrinology & Metabolism

Year:

2010

Language:

english

File:

PDF, 268 KB

english, 2010

21

Role of the prohormone convertase PC2 in the processing of proglucagon to glucagon

Yves Rouillé, Matteo Bianchi, Jean-Claude Irminger, Philippe A. Halban

Journal:

Year:

1997

Language:

english

File:

PDF, 644 KB

english, 1997

22

Distribution and metabolism of intravenously injected tritiated insulin in rats

Philippe A. Halban, Michael Berger, Robin E. Offord

Journal:

Year:

1979

Language:

english

File:

PDF, 871 KB

english, 1979

23

Autonomous and self-sustained circadian oscillators displayed in human islet cells

Pulimeno, P., Mannic, T., Sage, D., Giovannoni, L., Salmon, P., Lemeille, S., Giry-Laterriere, M., Unser, M., Bosco, D., Bauer, C., Morf, J., Halban, P., Philippe, J., Dibner, C.

Journal:

Year:

2013

Language:

english

File:

PDF, 573 KB

english, 2013

24

Proinsulin trafckin and processing in the pancreatic B cell

Halban, Philippe A.

Journal:

Trends in Endocrinology & Metabolism

Year:

1990

Language:

english

File:

PDF, 855 KB

english, 1990

25

Expression, phosphorylation and function of the Rab-GTPase activating protein TBC1D1 in pancreatic beta-cells

Rütti, Sabine, Arous, Caroline, Nica, Alexandra C., Kanzaki, Makoto, Halban, Philippe A., Bouzakri, Karim

Journal:

Year:

2014

Language:

english

File:

PDF, 793 KB

english, 2014

26

RESISTANCE AGAINST SUBCUTANEOUS INSULIN SUCCESSFULLY MANAGED WITH APROTININ

Müller, WalterA., Taillens, Claude, Léreret, Serge, Berger, Michael, Philippe, Jacques, Halban, PhilippeA., Offord, R.E.

Journal:

Year:

1980

Language:

english

File:

PDF, 284 KB

english, 1980

27

The ratio of mouse insulin I:insulin II does not reflect that of the corresponding preproinsulin mRNAs

Wentworth, Bruce M., Rhodes, Christopher, Schnetzler, Bruno, Gross, David J., Halban, Philippe A., Villa-Komaroff, Lydia

Journal:

Molecular and Cellular Endocrinology

Year:

1992

Language:

english

File:

PDF, 1.21 MB

english, 1992

28

A clathrin-coated, golgi-related compartment of the insulin secreting cell accumulates proinsulin in the presence of monensin

Orci, Lelio, Halban, Philippe, Amherdt, Mylène, Ravazzola, Mariella, Vassalli, Jean-Dominique, Perrelet, Alain

Journal:

Year:

1984

Language:

english

File:

PDF, 16.09 MB

english, 1984

29

Production of insulin antibodies by mice rejecting insulin transfected cells

Gross, David J., Bonner-Weir, Susan, Villa-Komaroff, Lydia, Halban, Philippe A., Ikegami, Hiroshi, Soeldner, J.Stuart, Eisenbarth, George S., Ziegler, Anette G., Vardi, Pnina

Journal:

Journal of Autoimmunity

Year:

1989

Language:

english

File:

PDF, 657 KB

english, 1989

30

PO15 Rôle de l’horloge circadienne dans la fonction de l’îlot pancréatique humain

Dibner, C., Pulimeno, P., Mannic, T., Sage, D., Unser, M., Salmon, P., Giovannoni, L., Bosco, D., Halban, P., Philippe, J.

Journal:

Diabetes & Metabolism

Year:

2013

Language:

french

File:

PDF, 70 KB

french, 2013

31

Partial Diversion of a Mutant Proinsulin (B10 Aspartic Acid) from the Regulated to the Constitutive Secretory Pathway in Transfected AtT-20 Cells

David J. Gross, Philippe A. Halban, C. Ronald Kahn, Gordon C. Weir and Lydia Villa-Komaroff

Journal:

Proceedings of the National Academy of Sciences

Year:

1989

Language:

english

File:

PDF, 1.28 MB

english, 1989

32

Inositol 1,4,5-Trisphosphate Receptor Subtype 3 in Pancreatic Islet Cell Secretory Granules Revisited

Mariella Ravazzola, Philippe A. Halban and Lelio Orci

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 1009 KB

english, 1996

33

Newly Synthesized Proinsulin/Insulin and Stored Insulin Are Released from Pancreatic B Cells Predominantly via a Regulated, Rather Than a Constitutive, Pathway

Christopher J. Rhodes and Philippe A. Halban

Journal:

The Journal of Cell Biology

Year:

1987

Language:

english

File:

PDF, 1.73 MB

english, 1987

34

Nonconverted, Amino Acid Analog-Modified Proinsulin Stays in a Golgi-Derived Clathrin-Coated Membrane Compartment

Lelio Orci, Philippe Halban, Mylene Amherdt, Mariella Ravazzola, Jean-Dominique Vassalli and Alain Perrelet

Journal:

The Journal of Cell Biology

Year:

1984

Language:

english

File:

PDF, 2.56 MB

english, 1984

35

pH-Independent and -Dependent Cleavage of Proinsulin in the Same Secretory Vesicle

Lelio Orci, Philippe Halban, Alain Perrelet, Mylène Amherdt, Mariella Ravazzola and Richard G. W. Anderson

Journal:

The Journal of Cell Biology

Year:

1994

Language:

english

File:

PDF, 1.23 MB

english, 1994

36

β-Cell Failure in Type 2 Diabetes: Postulated Mechanisms and Prospects for Prevention and Treatment

Halban, Philippe A., Polonsky, Kenneth S., Bowden, Donald W., Hawkins, Meredith A., Ling, Charlotte, Mather, Kieren J., Powers, Alvin C., Rhodes, Christopher J., Sussel, Lori, Weir, Gordon C.

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2014

Language:

english

File:

PDF, 135 KB

english, 2014

37

Current Status of Islet Cell Replacement and Regeneration Therapy

Halban, Philippe A., German, Michael S., Kahn, Steven E., Weir, Gordon C.

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2010

Language:

english

File:

PDF, 112 KB

english, 2010

38

β-Cell Failure in Type 2 Diabetes: Postulated Mechanisms and Prospects for Prevention and Treatment

Halban, Philippe A., Polonsky, Kenneth S., Bowden, Donald W., Hawkins, Meredith A., Ling, Charlotte, Mather, Kieren J., Powers, Alvin C., Rhodes, Christopher J., Sussel, Lori, Weir, Gordon C.

Journal:

Year:

2014

Language:

english

File:

PDF, 849 KB

english, 2014

39

Fractalkine (CX3CL1), a new factor protecting β-cells against TNFα

Rutti, Sabine, Arous, Caroline, Schvartz, Domitille, Timper, Katharina, Sanchez, Jean-Charles, Dermitzakis, Emmanouil, Donath, Marc Y., Halban, Philippe A., Bouzakri, Karim

Journal:

Molecular Metabolism

Year:

2014

Language:

english

File:

PDF, 2.42 MB

english, 2014

40

Glucose-Stimulated Insulin Secretion Is Coupled to the Interaction of Actin with the t-SNARE (Target Membrane Soluble N -Ethylmaleimide-Sensitive Factor Attachment Protein Receptor Protein) Complex

Thurmond, Debbie C., Gonelle-Gispert, Carmen, Furukawa, Megumi, Halban, Philippe A., Pessin, Jeffrey E.

Journal:

Molecular Endocrinology

Year:

2003

Language:

english

File:

PDF, 517 KB

english, 2003

41

Short Term Exposure of Beta Cells to Low Concentrations of Interleukin-1β Improves Insulin Secretion through Focal Adhesion and Actin Remodeling and Regulation of Gene Expression

Arous, Caroline, Ferreira, Pedro G., Dermitzakis, Emmanouil T., Halban, Philippe A.

Journal:

Journal of Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 4.86 MB

english, 2015

42

50 years forward: beta cells

Halban, Philippe A.

Journal:

Year:

2015

Language:

english

File:

PDF, 199 KB

english, 2015

43

Role of the Rho-ROCK (Rho-Associated Kinase) Signaling Pathway in the Regulation of Pancreatic β-Cell Function

Hammar, Eva, Tomas, Alejandra, Bosco, Domenico, Halban, Philippe A.

Journal:

Year:

2009

Language:

english

File:

PDF, 297 KB

english, 2009

44

Induction of CXCL1 by Extracellular Matrix and Autocrine Enhancement by Interleukin-1 in Rat Pancreatic β-Cells

Ribaux, Pascale, Ehses, Jan A., Lin-Marq, Nathalie, Carrozzino, Fabio, Böni-Schnetzler, Marianne, Hammar, Eva, Irminger, Jean-Claude, Donath, Marc Y., Halban, Philippe A.

Journal:

Year:

2007

Language:

english

File:

PDF, 436 KB

english, 2007

45

The skeleton in the closet: actin cytoskeletal remodeling in β-cell function

Arous, Caroline, Halban, Philippe A.

Journal:

AJP Endocrinology and Metabolism

Year:

2015

Language:

english

File:

PDF, 2.09 MB

english, 2015

46

Differential Gene Expression in Well-Regulated and Dysregulated Pancreatic β-Cell (MIN6) Sublines

Lilla, Valérie, Webb, Gene, Rickenbach, Katharina, Maturana, Andres, Steiner, Donald F., Halban, Philippe A., Irminger, Jean-Claude

Journal:

Year:

2003

Language:

english

File:

PDF, 253 KB

english, 2003

47

The GM2-1 Ganglioside Islet Autoantigen in Insulin-Dependent Diabetes Mellitus Is Expressed in Secretory Granules and Is Notβ -Cell Specific 1

Dotta, Francesco, Previti, Marcello, Neerman-Arbez, Marguerite, Dionisi, Sabrina, Cucinotta, Domenico, Lenti, Luisa, Di Mario, Umberto, Halban, Philippe A.

Journal:

Year:

1998

Language:

english

File:

PDF, 314 KB

english, 1998

48

Dual Effect of Cell-Cell Contact Disruption on Cytosolic Calcium and Insulin Secretion

Jaques, Fabienne, Jousset, Hélène, Tomas, Alejandra, Prost, Anne-Lise, Wollheim, Claes B., Irminger, Jean-Claude, Demaurex, Nicolas, Halban, Philippe A.

Journal:

Year:

2008

Language:

english

File:

PDF, 470 KB

english, 2008

49

SNAP-25 Is Expressed in Islets of Langerhans and Is Involved in Insulin Release

Karin Sadoul, Jochen Lang, Cesare Montecucco, Ulrich Weller, Romano Regazzi, Stefan Catsicas, Claes B. Wollheim and Philippe A. Halban

Journal:

The Journal of Cell Biology

Year:

1995

Language:

english

File:

PDF, 3.42 MB

english, 1995

50

Short term exposure of beta cells to low concentrations of interleukin-1β improves insulin secretion through focal adhesion and actin remodeling and regulation of gene expression.:

Arous, Caroline, Ferreira, Pedro G., Dermitzakis, Emmanouil T., Halban, Philippe A.

Journal:

Journal of Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 928 KB

english, 2015